Est.1979
Providing Integrated Research Solutions in Preclinical Biology
| Study Title | Reference Drug | End point Parameters |
|---|---|---|
| Subcutaneous Xenograft models using athymic Nude and SCID Mice | Cytotoxic Agents | Tumor Volume, Growth Inhibition, %T/C, Growth Delay, Body weight |
| Syngenic tumour models using BALB/c and C57BL6 Mice | Cytotoxic Agents | Tumor Volume, Growth Inhibition, %T/C, Growth Delay, Body weight |
| Surgical Orthotopic models using Nude and SCID Mice | Cytotoxic Agents | Survival proportion, Body weight, Histology, Clinical sign |
| Matrigel Plug Assay for In-vivo Angiogenesis | Cytotoxic Agents | Hemoglobin content, Histology, IHC |
| In-vivo Anti-Metastasis assay using B16F10 Intravenous models | Cytotoxic Agents | Lung melanoma colony count, Body weight , clinical sign, Histology |
| In-vivo anti-Leukemia activity using NOD SCID mice model | Cytotoxic Agents | Clinical score, Body weight change, % Increased Life span, Kaplan Meier curve, CD 45 level in whole blood |
| Tumorigenesis assay using using athymic Nude and SCID Mice | Cytotoxic Agents | Tumor Volume, Growth rate, % take up , Tumor volume doubling time |
| AOM-DSS induced colon cancer in C57BL6 Mice | Cytotoxic Agents | Body weight, clinical sign,Polyps count, Cytokine estimation, Histology, IHC |
| DMBA+ Croton Oil induced skin cancer model in mice | Cytotoxic Agents | Body weight, Polyps count, & Histology |