Est.1979
Providing Integrated Research Solutions in Preclinical Biology
| Study Title | Reference Drug | End point Parameters |
|---|---|---|
| TNBS induced Inflammatory Bowel Disease (IBD) Model in Mice | Sulphasalazine | Colitis clinical score, Body weight, Cytokine (IL1beta, TNF alpha) level in colon tissue & serum, Histology |
| LPS induced Sepsis Model in Mice | Dexamethasone | Cytokine ( TNF alpha & IL6)levels in serum |
| LPS induced Lung inflammation model in Mice | Dexamethasone | Cytokine (TNF alpha & IL6) levels in serum & Lung tissue homogenate |
| Monosodium Iodoacetate (MIA)-induced Osteoarthritis (OA) in Wistar Rats | NSAID | Pain sensitivity by Pressure application in knee joint, Collagen at knee joint , knee joint histology etc |
| DSS induced ulcerative colitis model in mice | Sulphasalazine | UC score, Body weight, Cytokine level in colon tissue & serum, Histology |
| Anti-Inflammatory Activity by Carrageenan Induced Paw Edema using Rat / Mice | Indomethacin | Absolute paw volume, Edema, % activity & PGE2 COX in paw tissue or serum, Pain sensitivity |
| Anti-Arthritic Potential of Test Item on Rat Adjuvant (CFA) Induced Arthritis | Methotexate, Dexamethazone | Arthritis Score, Paw volume, Body weight, Serum Biomarkers (TNF alpha, IL6 , CRP etc..) , Radiography & Histology of Hind paw |
| Collagen-induced Arthritis in Rats | Methotexate, Dexamethazone | Arthritis Score, Paw volume, Body weight, Serum Biomarkers (TNF alpha, IL6 , CRP etc..) , Radiography & Histology of Hind paw |
| Ceccal Slurry induced SIRS Model in rats | Dexamethazone | Clinical sign score, Body weight, survival analysis, Cytokine level (TNF alpha, IFN gamma, IL6, IL1beta etc..)is serum and variuos tissues & Histology |