Charcoal Meal test : Gastric Emptying using Rat/ Mice Model |
Metaclopramide |
GI transit, Meal travel distance, % Activity |
Anti-Ulcer activity using indomethacin induced gastric ulcer model in rats |
Ranitidine |
Ulcer area, ulcer count, score, histology of stomach, total acidity,Gastric PH |
Anti-Ulcer activity ( Anti-secretory & Cytoprotective) using pyrolus ligation model in rats |
Omeprazole |
Ulcer area, ulcer count, score, histology of stomach, total acidity,Gastric PH |
Ulcerogenic Potential of Test Item using Rat Model |
NA |
Ulcer area, ulcer count, score, histology of stomach |
Loperamide induced Constipation model in rats |
Procloopride |
Fecal count, Fecal weight, wet-dry weight ratio , Histology of colon |
5FU & Physical damage induced mucositis using hamster |
Dexamethazone |
Mucosal scoring, Imagining, Histology of cheek pouch , Cytokine estimation |