DERMATOLOGY

Study Title Reference Drug End point Parameters
Anti-psoriatic Potential in Imiquimod (IMQ)-induced skin inflammation in mice Betamethasone Cytokine (IL23, IL17, TNF alpha etc..) levels in serum & skin, Clinical score, biopsy weight, histology of skin
Anti-psoriatic Potential: TPA induced Skin Inflammation Model in Mice Betamethasone Cytokine levels in serum & skin, Clinical score, biopsy weight, histology of skin
Atopic Dermatitis Using Oxazolone in BALB/c Mice Betamethasone, Tacrolimus Cytokine ( IFN gamma, TNF alpha, IL5, etc..) levels in serum & skin, Clinical score, biopsy weight, histology of skin
Antipruritic effect using histamine-induced itching model in mice Ant-histaminic No. of scratch , % Activity, serum histamine
Wound healing activity using Rat Incision Model Siver suphadiazine Growth factor (KGF & VEGF) in skin tissue & skin Histology
Wound healing activity using Rat excision Model Siver suphadiazine Wound area, Wound contraction, Growth factor (KGF & VEGF) in skin tissue & skin Histology
Pressure – wound (Bed sore) model in Rats Phenytoin Wound score, Growth factor (VEGF & KGF) in skin tissue & skin Histology