dabur

Est.1979

Providing Integrated Research Solutions in Preclinical Biology

Oncology

Study Title Reference Drug End point Parameters
Subcutaneous Xenograft models using athymic Nude and SCID Mice Cytotoxic Agents Tumor Volume, Growth Inhibition, %T/C, Growth Delay, Body weight
Syngenic tumour models using BALB/c and C57BL6 Mice Cytotoxic Agents Tumor Volume, Growth Inhibition, %T/C, Growth Delay, Body weight
Surgical Orthotopic models using Nude and SCID Mice Cytotoxic Agents Survival proportion, Body weight, Histology, Clinical sign
Matrigel Plug Assay for In-vivo Angiogenesis Cytotoxic Agents Hemoglobin content, Histology, IHC
In-vivo Anti-Metastasis assay using B16F10 Intravenous models Cytotoxic Agents Lung melanoma colony count, Body weight , clinical sign, Histology
In-vivo anti-Leukemia activity using NOD SCID mice model Cytotoxic Agents Clinical score, Body weight change, % Increased Life span, Kaplan Meier curve, CD 45 level in whole blood
Tumorigenesis assay using using athymic Nude and SCID Mice Cytotoxic Agents Tumor Volume, Growth rate, % take up , Tumor volume doubling time
AOM-DSS induced colon cancer in C57BL6 Mice Cytotoxic Agents Body weight, clinical sign,Polyps count, Cytokine estimation, Histology, IHC
DMBA+ Croton Oil induced skin cancer model in mice Cytotoxic Agents Body weight, Polyps count, & Histology
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