dabur

Est.1979

Providing Integrated Research Solutions in Preclinical Biology

Modules

In Vitro Pharmacology

Others

In Vitro Model for identification of anti-rhinitic compounds
ModelEvaluation of anti-rhinitic activity
Test system
  • Human nasal epithelial cell line (RPMI 2650)
  • Human airway epithelial cell line (A549)
Method
  • Treatment of cells with test compounds
  • Induction of inflammatory conditions by treatment with appropriate stimulant (HDM extract/LPS)
  • Assessment of TGF-ß2 secretion in RPMI 2650 cell line
  • Assessment of IL-6 & IL-8 in A549 cell line
End pointsQuantitation of inflammatory cytokines

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