Est.1979
Providing Integrated Research Solutions in Preclinical Biology
| Study Title | Reference Drug | End point Parameters |
|---|---|---|
| Anti-Nociceptive activity in the CCI-peripheral neuropathy Rat Model | Gabapentin | Pain sensitivity by Pressure application, % Activity |
| Chemotherapy Vincristine-induced Peripheral Neuropathy (CIPN) in Rats | Gabapentin | Pain sensitivity by Pressure application, % Activity, Cytokine estimation |
| MPTP induced model of Parkinson’s disease in Mice | L-DOPA | Pole Test, Traction Test, Dopamine level in brain , Brain Histology |
| Anti-dementia activity using Scopolamine induced rat/mice model | Donepzil Hydrocloride | Body weight, Passive Avoidance Test, Acetylcholinestrase, Neural growth factor, TNF -alpha estimation and Histopathology of Brain |
| Anti-dementia activity using STZ (Intracerebroventricular) induced rat/mice model | Donepzil Hydrocloride | Body weight, Morris Water Maze Test , Y Maze and Histopathology of Brain |
| Anti-anxeity activity using Elevated Plus Maze Test using Rat & Mice | Diazepam | Time spent in open & close arm to analyse Anxiety |
| Anti-depressant activity using Force swim test in Rats | Imipramine | Body weight, Feed intake, Actimeter, Force swim Test, Open field Test, Adrenal weight, Corticosterone estimation. |
| Anti-depressant activity using tail suspension test using Rat & Mice | Imipramine | Body weight, Feed intake, Actimeter, Elevated Plus maze, Open field Test, Corticosterone estimation. |
| Muscle relaxant activity using rota rod test in rat & Micel | — | RPM-Time of Fall from Rotarod in Sec. |
| Learning & memory potential using Morris water maze test in Rats | — | Time spent in NEWS zones and Time to reach hidden platform in water maze (MWM), Acetlycholine and Dopamine levele estimation to analyse memory |
| Anti-stress activivty using Unpredicatable Chronic Stress (UCS) Model in Rats | Imipramine | Body weight, Feed intake, Actimeter, Elevated Plus maze, Open field Test, Adrenal weight and Corticosterone, Serotonin, Anti-oxidant level estimation. |
| Learning & memory potential using Y Maze test | — | Time spent in Center and XYZ zone, Acetlycholine and Dopamine levele estimation to analyse Leaning and Memory potential. |