GI HEALTH

Study Title Reference Drug End point Parameters
Charcoal Meal test : Gastric Emptying using Rat/ Mice Model Metaclopramide GI transit, Meal travel distance, % Activity
Anti-Ulcer activity using indomethacin induced gastric ulcer model in rats Ranitidine Ulcer area, ulcer count, score, histology of stomach, total acidity,Gastric PH
Anti-Ulcer activity ( Anti-secretory & Cytoprotective) using pyrolus ligation model in rats Omeprazole Ulcer area, ulcer count, score, histology of stomach, total acidity,Gastric PH
Ulcerogenic Potential of Test Item using Rat Model NA Ulcer area, ulcer count, score, histology of stomach
Loperamide induced Constipation model in rats Procloopride Fecal count, Fecal weight, wet-dry weight ratio , Histology of colon
5FU & Physical damage induced mucositis using hamster Dexamethazone Mucosal scoring, Imagining, Histology of cheek pouch , Cytokine estimation